Test directory: Chromosome Analysis, POC reflex SNP

Ordering Code 8635
Test Name Chromosome Analysis, POC reflex SNP
Alias Chromosome Analysis, Products of Conception (POC) With
Reflex to SNP Microarray (Reveal (R))
Karyotyping, POC
Preferred Specimen Tissue, skin, ovarian biopsy, products of conception, placental biopsy
Preferred Container Sterile container containing sterile Ringer's lactate or
Hanks' balanced salt solution or transport media provided by the cytogenetic laboratory; do not use urine containers for shipping.
Optimum Volume 75-100 mg of tissue of 3-4 mm POC
Collection Instructions Please include clinical information, previous cytogenetic report, or karyotype. If prior NIPT studies have been performed, include copy of the report
Clinical Questionnaire for SNP Microarray is required
https://www.labcorp.com/resource/clinical-questionnaire-for- snp-microarray
Aseptically obtain a small piece of tissue with subepidermal layers. Best results are obtained from placental villi, which remain viable much longer than fetal tissue. This is especially true in stillborn cases in which both cord blood and tissue samples are often not viable. If specimen is a product of conception, submit biopsies in a sterile tube with sterile Ringer's lactate, Hanks' balanced salt solution, or LabCorp transport medium.
Transport Requirements Oahu: Refrigerated
Airline: Refrigerated
Specimen Stability Ambient: Not Stable
Refrigerated: 72 Hours
Frozen: Not Stable
Optimum transport <72 hours. Do not reject. Send specimen to lab for viability determination.
Rejection Criteria Gross contamination; necrotic tissue; specimen in fixative
Avail. Stat NO
Analytic Time 24 Days
Methodology Tissue culture following enzymatic digestion of tissue
Standard harvesting and G-banding procedures are used with 20 metaphases examined and two karyotypes prepared. If tissue fails to grow for cytogenetic analysis, SNP microarray analysis is performed
Reference Lab  Labcorp

Reference range(s)

Component Age Male Norm Male Critical Low Male Critical High Female Norm Female Critical High Female Critical Low Units Add'l info
Cells Counted ALL See report.
Cells Karyotyped ALL See report.
Cells Analyzed ALL See report.
GTG Band Resolution Achieved ALL See report.
Cytogenetic Result ALL See report.
Cytogenetic Interpretation ALL See report.
Specimen Type ALL See report.
Director Review ALL See report.
Reflex ALL See report.
PDF ALL See report.